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Oral administration of Akkermansia muciniphila reduces P.g- and F.n -induced periodontal bone loss and inflammation by modulating host immune responses (increasing IL-10 and decreasing IL-12) and strengthening mucosal barriers in both the gingiva and intestine (Huck et al., 2020

TIMP-1 via TWIST1 induces EMT phenotypes in human breast epithelial cells

The peptide activates transforming growth factor-beta (TGF-) signaling cascades, leading to enhanced collagen I and III synthesis through increased procollagen C-proteinase activity

They are generally safe for short-term use but can interact with certain medications and should not be used for extended periods

Unlike small-molecule drugs that often have broad, systemic effects, peptides are large enough to target specific biological pathways yet small enough to penetrate tissues and reach injured areas effectively

However, its relationship with hair loss remains virtually unknown