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We interpret this accumulation as a consequence of spliceosome stalling at the B to B act transition

This current study by Ekarattanawong et al

As yeast eats through its growth medium, it leaves behind a nutrient soup of amino acids, peptides, vitamins, and minerals

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Significantly, enhanced transamination and aspartate synthesis in K-Ras-driven cancer cells are important in the promotion of nucleotide biosynthesis 184 and maintenance of redox balance 29