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A new hierarchy for patient care and clinical decisions exists as these drugs exhibit more average weight loss and potentially fewer side effects
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These findings suggest that GIP but not GLP-1RA may improve glucose disposal by ameliorating peripheral insulin sensibility and glucose utilization, while GIP added on to GLP-1RA may reduce food intake with a combined effect resulting in improvement of glucose control and weight loss
The usual intuition that a higher dose is at least a stronger version of the same thing is simply false here
Real-life example A woman in her thirties who needed B12 injections after gastric surgery was anxious about soreness
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