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Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle

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In a cohort of 155 patients with paroxysmal AF, with a mean age of 56.8 years, individuals with significant reductions in leukocyte telomere length exhibited a higher recurrence rate of AF (HR 2.68, 95% CI 1.504.79, P = 0.001), along with more pronounced left atrial enlargement, indicating severe atrial remodeling (Pan et al., 2019)

Re-assessment of the influence of polymorphisms of phase-II metabolic enzymes on renal cell cancer risk of trichloroethylene-exposed workers

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