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Real-time PCR was performed with the SYBR Green Real-time PCR Master Mix (Toyobo Co., Ltd.) on the 7500 Real-time PCR system (Life Technologies, Carlsbad, CA, USA)

A lack of this important antioxidant can also negatively impact vision, skin health, and clarity of thought [3]

The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are nuclear receptors that regulate genes involved in bilirubin and bile acid detoxification

Interestingly, a follow-up study found that neither pre- nor post-treatment of metformin against APAP hepatotoxicity inhibited JNK activation or its mitochondrial translocation [31], [32]

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