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they were further screened to examine their inhibitory role by going through docking studies using AUTODOCK software

PMCID: PMC4966972

Sections were stained with hematoxylin and eosin (H&E)

In rat coronary artery smooth muscle cells, treatment with liraglutide inhibited VSMC phenotypic transition induced by advanced glycation end products (AGEs), through blocking the nuclear factor-B (NF-B) signaling pathway and activating the protein kinase A (PKA) signaling pathway

The following formula illustrates the relationship: Concentration (mg/mL) = Vial content (mg) Volume of bacteriostatic water added (mL) Illustrative examples: 2 mg vial + 1 mL bacteriostatic water = 2 mg/mL 2 mg vial + 2 mL bacteriostatic water = 1 mg/mL 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL Note that the concentrations in the examples above differ from one another

Pancreatitis is a rare but serious potential complication associated with GLP-1 agonist use