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JAAOS Global Research & Reviews

If youre considering use: Be aware of purity, legality, and lack of human safety data

Combining ibuprofen with certain herbal supplements that have blood-thinning effects could increase the risk of bleeding

Standard treatments remove or close off damaged veins

Analytical testing confirms greater than 99.8 % purity , assay content verified at 55.1 mg and endotoxin levels below 0.001 EU/mg

Last reviewed: June 6, 2026 Last updated: June 6, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations