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Digestive Symptoms Oral or injectable components may be associated with digestive discomfort, appetite changes, nausea or changes in bowel habits in some patients

Education confirmation (initial based education points and patient responsibilities for safer monitoring)

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Even when symptoms have quieted, this is when connective tissue is thought to be strengthening rather than just feeling better

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Second, study populations have been heterogeneous with respect to diabetes status, obesity, renal function, baseline cardiovascular disease, and HF phenotype, which may limit generalizability