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Anal Biochem 98(1):154159 Massa CM, Liu Z, Taylor S, Pettit AP, Stakheyeva MN, Korotkova E, Popova V, Atochina-Vasserman EN, Gow AJ (2021) Biological mechanisms of S-nitrosothiol formation and degradation: how is specificity of S-nitrosylation achieved

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[256] identified labile copper sources in the developing retina, and demonstrated that they modulate spontaneous activity of neural circuits via the copper transporter Ctr1, referred to as a copper ion channel ( see also section The source-target-physiology scheme for therapeutic intervention )

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That framing changes what continued treatment is for: holding a result rather than extending it