Because tirzepatide and semaglutide activate incretin hormone pathways differently, people often wonder whether one medication behaves differently than the other at lower doses
doi: 10.3389/fendo.2024.1528457 Received 14 November 2024 Accepted 30 December 2024 Published 21 January 2025 Volume 15 - 2024 Edited by Claire Joanne Stocker, Aston University, United Kingdom Reviewed by Wael Sidrak, Abou Seifein Diabetes & Endocrine Center, Egypt Frederic Illouz, CHU Angers, France Christine Trapp, Connecticut Childrens Medical Center, United States Updates Copyright 2025 Koceva, Mleku Kozamernik, Jane, Herman, Ferjan and Jensterle
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This, however, still accounted for less than a third of the cardiovascular benefit seen in patients who took semaglutide. Not just a weight loss drug Semaglutide benefits heart disease patients even with only modest weight increase and should be part of cardiometabolic disease management and not just considered as a weight loss drug
[DOI] [PubMed] [Google Scholar] 161.Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC