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RNA sequencing To study the consequences of 5-OP accumulation AB6302 strain was grown in SD medium containing 5mM 5-oxoproline (test) or 0mM 5-oxoproline (control)

RNA (1 g) was reverse transcribed using PrimeScript reverse transcriptase master mix (TaKaRa)

J Neurosci Res 2007

While GSH donates electrons to counter free radicals and reactive oxygen species, it turns into GSSG, the inactive and oxidized form of glutathione

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In short, an injection will provide a higher dose of B12 at regular intervals, whilst oral supplements have a lower dosage and can be taken every day