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Nat Rev Nephrol 17:417433 Ye Y, Chen A, Li L, Liang Q, Wang S, Dong Q (2022) Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification

The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme

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Over-the-counter NSAIDs (like ibuprofen , often prescribed at higher doses) also contribute

They are short chains of amino acids that act as signaling molecules in the body, influencing processes like hormone release, tissue repair and metabolism