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Magnetic resonance imaging studies of patients included in a Phase 1B/2A clinical trial showed slowing of the rate of decline in hippocampal volume in the treated group and evidence of increased hippocampal volume in APOE4 gene carriers

There are some important contraindications for taking GLP-1 medications: a severe allergic reaction to a GLP-1 medication in the past a history of pancreatitis pregnancy or breastfeeding a history of medullary thyroid cancer or multiple endocrine neoplasia type 2 in yourself or an immediate family member Finally, cost and access need to be considered

The goal is sustainable, medically supported weight loss and better health over time

Moreover, it is not advisable for individuals with type 1 diabetes or those seeking treatment for diabetic ketoacidosis

Other possible side effects are gallstones and loss of muscle mass

Additional Information When is this change effective