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Data obtained by the AVANT trial of adjuvant bevacizumab in colorectal cancer shows evidence of higher incidence of relapses and deaths in bevacizumab treated patients due to disease progression suggesting an increased tumor aggressiveness after anti-angiogenic therapy [288]

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The clinical efficacy of glutathione is also supported by large-scale patient-reported outcomes among people managing the overlapping triad of Long COVID, ME/CFS, and POTS/dysautonomia, where glutathione therapies are frequently rated among the more helpful interventions for this complex neuroimmune symptom cluster