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High-throughput screening (HTS) and phenotypic assays can be applied to profile natural compounds across many potential targets or cellular pathways, generating data that are then integrated into drugtarget networks

In this way, we aim to characterize what is currently known about T2D pathogenesis and highlight key areas where more data are needed to understand this disease

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The oxidized form of glutathione (glutathione disulfide), which is generated during the reduction of hydroperoxides by GPX4, is recycled by glutathione reductase and NADPH/H +

doi:10.18632/aging.102682