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GLP-1 agonists (glucagon-like peptide-1 receptor agonists) work by mimicking a hormone your body naturally produces to manage blood sugar and digestion

GLP-1 medications may help stabilize some of these variables

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doi: 10.1016/j.trecan.2023.02.001 101 Calvillo-RodrguezKMLorenzo-AnotaHYRodrguez-PadillaCMartnez-TorresACScott-AlgaraD

GLP-1 coverage decisions are creating pressure to show long-term outcomes

~200 in mice) and lipid metabolism pathways (e.g., bile acid synthesis) are different, rendering animal study results non-translatable to humans (8890)