Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, bloodCNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis
This should not be construed as a contraindication to the use of AOXs
The critical need for production of NADPH, via the pentose phosphate pathway, is especially true in red blood cells because there are no other NADPH-producing reactions in these cells and they are extremely sensitive to oxidative damage
doi: 10.3389/fmicb.2022.871645
Unlike an overdose in humans, it is rarely liver damage that is the cause of death, instead methaemoglobin formation and the production of Heinz bodies in red blood cells inhibit oxygen transport by the blood, causing asphyxiation
SPJ : the official publication of the Saudi Pharmaceutical Society