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Major modifications for 2025 As outlined in the 2025 Summary of Major Modifications and Explanatory Notes, the major modifications for 2025 include the following: Further examples were added to the following substance classes to help athletes and their entourage better identify prohibited substances: S0

CagriSema clinical trial results The REDEFINE 1 trial enrolled adults with obesity or overweight (BMI of 30 or greater, or 27 or greater with at least one weight-related comorbidity) without type 2 diabetes

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Suggested Use Take 1 capsule per day, or as directed by your health-care practitioner

Having relationships with backup providers and understanding your insurance options provides protection against this scenario

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