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Deficiency in B12 can lead to neurological problems, such as tingling or numbness in the hands and feet, difficulty walking, and memory impairment

Compounded lipotropic preparations are not reviewed or approved by the FDA for safety, effectiveness, or quality before they are marketed

Carcinogenesis, Mutagenesis, Impairment of Fertility Studies of carcinogenicity, mutagenesis, or impairment of fertility have not been performed with hydroxocobalamin

While there is some animal data and limited human research supporting its potential use case, its safety and efficacy profile is still not well-understood

Studies indicate that adequate levels of B12 may reduce the risk of neurodegenerative diseases like Alzheimers

(Scientific Reports, 2022) showed that the combination of 5-Amino-1MQ + caloric restriction establishes a distinct cecal microbial profile, normalizing the microbiome to the levels of lean control mice, whereas caloric restriction alone fails to do so