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Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-alpha

Deboever N, Al-Tashi Q, Eisenberg M, Saad MB, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth J, Swisher SG , Vaporciyan AA, Walsh GL, Wu J, Rajaram R

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Radioimmunoassays in tissues from rats [52], pigs [53], and humans [54] then established a distinct profile of proglucagon-derived peptides (PGDPs) in the pancreas and the intestine with production of glucagon and one large fragment (major proglucagon fragment

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