It is a tool that may help quiet the immune alarm in the gut while other parts of the plan do their work
Infect Immun 71:70697078
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Macpherson AJ, Uhr T (2004) Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
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Therefore, higher proinsulin levels in the thymus are hypothesized to induce negative selection of insulin-specific thymocytes, thereby increasing tolerance to insulin autoantigens ( INS locus in central tolerance and demonstrate that genetic variants can impact both disease risk and progression, underscoring the need to investigate other non-HLA genes associated with T1D