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Ren et al., 2018

On the other hand, extractions under pressure affect the properties of the solvents themselves by changing their polarity, viscosity and diffusivity, thus improving the efficiency of the process

High-dose use While trials have tested up to 1200mg/day (even as high as 2400mg/day) and illustrated safety, some report higher rates of gastrointestinal side effects, dizziness, and skin reactions at these levels.14 28 38 Additionally, these higher doses are often short-term (35 weeks) and used under clinical supervision

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Changes may take a few months, but many people notice clearer skin and slower hair growth over time