Its a triple agonist, meaning it activates not one, but three key receptors in your body: GLP-1, GIP, and glucagon receptors
That said, semaglutide still produces clinically meaningful, life-improving weight loss for the majority of patients
For a 180-pound (82 kg) person, that translates to roughly 98 to 123 grams of protein daily
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Thats a direct result of the medications ~7-day half-life and slow elimination, as described in clinical references like StatPearls
Those with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasias should not use them