This window allows the peptide to reach peak plasma concentration and begin binding NNMT enzymes before dietary nicotinamide from food enters the system
So, youre going to push the needle straight in
Regardless, for extra precaution, some recommend breastfeeding before the Botox treatment along with storing some milk, and then pump and dump any milk produced in the subsequent 12 hours after Botox (so plenty of milk should be saved ahead of time)
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(PubMed) Hand I, Noble L, Abrams SA
It takes between 48 and 72 hours after a B12 shot for the effects to become apparent
