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Special Considerations for Dual-Receptor Agonists Switching to or from tirzepatide may temporarily impact weight loss or blood sugar control due to its dual-receptor mechanism

All existing interest and discussion surrounding this peptide existstrictly within experimental and research frameworks

Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbll T, SUSTAIN-6 Investigators

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Excessive deposition of stiff, cross-linked ECM components including type I/III collagen, fibronectin, and HA alters the biomechanical properties of the hepatic microenvironment

BasuRay, S., Smagris, E., Cohen, J