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Open K ATP channels are postulated to protect skeletal muscle against energy depletion in fatigue [115]

Wilding JPH, et al

Thus, targeting the NRF2 pathway holds great potential for being a disease-modifying treatment

doi: 10.1016/j.physbeh.2008.04.018 15 BurmeisterMABrownJDAyalaJEStoffersDASandovalDASeeleyRJet al

However, the restoration of hepatic enzyme production over weeks could theoretically alter metabolism of drugs processed by the liver, potentially requiring dose adjustments for medications with narrow therapeutic windows

It inhibits the proliferation of cancer cells and increases apoptosis (programmed cell death) in cancer tissues