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Additionally, the free (unbound) concentration of certain drugs can decrease during pregnancy due to a notable drop of albumin and alpha-1-acid glycoprotein concentration (Murphy et al

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Many patients with treatment resistant depression who supplement their SSRIs with methylfolate report improvements in the efficacy of their antidepressants (4)

Lam NYL, Rainer TH, Chiu RWK, Lo YMD

Compounding allows pharmacists to customize delivery routes and concentrations to meet the unique needs of individual patients when commercially available products may not be the right fit

On the other hand, inability to eat even small meals, severe nausea lasting more than a few days after dose escalation, and significant dizziness or lightheadedness suggest the dose is too high