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For a contrasting case in which a peptide with a defined endogenous role and a more constrained but still incomplete mechanistic literature has nonetheless attracted sustained research interest, see the epitalon research brief

13 In the Brain Glutathione (GSH) is the antioxidant found in greatest quantity in the brain, and is found to be deficient in the brains of Alzheimers (AD) patients 14 15 16 (as well as Parkinsons patients)