Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent
MOTS-c should not be presented as a cure for fatigue, obesity, aging, or metabolic disease
Apparently, glutathionylation of the two class I GRXs by GSSG occurs even at very low GSSG amounts in freshly prepared GSH due to binding of GSSG in a way that favours a trigonal planar bipyramidal transition state 13,15
5 Exogenously supplied persulfide donors scavenge APEX2-generated intracellular radicals
A consistent, imperfect schedule outperforms a theoretically perfect schedule that you cannot maintain
They regulate appetite by acting on hunger and satiety centers in the brain They slow gastric emptying, allowing fullness to last longer They improve insulin sensitivity and blood sugar control They reduce impulsive eating and reward-driven cravings They quiet food noise that keeps many people stuck in cycles of overeating Most importantly, they give the body a chance to experience what normal hunger feels like again
