In bovine mammary-gland research, DES stimulated local cell proliferation at doses 10-fold lower than native IGF-1, demonstrating potency that is site-specific rather than systemic [11]
To make it absolutely clear, here is how the two peptides look when compared on a direct, consumer-relevant scale
The elevated growth hormone then boosts IGF-1 production in the liver and other tissues, which mediates many of GHs anabolic effects including increased protein synthesis and muscle growth, enhanced lipolysis and fat body function, improved bone density and tissue repair, enhanced collagen synthesis, and better sleep quality and healing
Skimping on sleep undermines IGF-1 LR3's potential effects
And for the positive feedback on the audio version that I narrated
Melatonin protects against cyclophosphamide-induced premature ovarian failure in rats