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Activation of GHRH-R adenylate cyclase increased intracellular cAMP activation of PKA phosphorylation of the transcription factor CREB increased transcription of the GH gene increased intracellular GH stores in vesicles

95% CI, 0.36-0.71)

Promotion of muscle cell differentiation and satellite cell support: IGF signaling is involved in the activation and differentiation of satellite cells, which are precursor cells responsible for muscle regeneration