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Replication of UV-damaged DNA: New insights into links between DNA polymerases, mutagenesis and human disease

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In fact, it has been observed that aberrant NFE2L2 transcript variants missing exon 2, or exons 2 and 3, are present in lung cancers and head and neck cancers

This signal profile is consistent with its clinical use context, in which prior radiation-related lung injury combined with immune activation may increase susceptibility to radiation pneumonitis and related pulmonary toxicities, with progression to severe outcomes in a subset of patients ( 025 0.96)

Dallas, S., Miller, D

These benefits stem from glutathiones fundamental role in cellular metabolism, its ability to neutralize harmful free radicals, and its crucial involvement in phase II detoxification processes