p53/SLC7A11 pathway This process is initiated when unsaturated FAs in cell membranes undergo catalytic lipid peroxidation, driven by divalent iron or esteroxygenases, leading to cell death (6971)
Medication name, dosage, and route
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The exact cause of neuronal death in Parkinson's remains incompletely understood, but contributing factors include oxidative stress, mitochondrial dysfunction, neuroinflammation, and abnormal protein aggregation (particularly alpha-synuclein)
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Evaluated for changes in body weight, fat mass, and waist circumference in obesity-related models