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Effects of glutamine and dietary fibers on GLP-1

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In this trial, individuals in the retatrutide 12 mg escalation group, at week 36, showed HbA1c reductions of up to 2.16%, i.e., 2359 mmol/mol

mRNA expression of proglucagon by mouse L-cells (STC-1) was also significantly reduced and supports the findings in the human cells

Biolo G, Toigo G, Ciocchi B, Situlin R, Iscra F, Gullo A, Guarnieri G: Metabolic response to injury and sepsis: changes in protein metabolism