doi: 10.1038/s41467-019-11638-3 69 DopkinsNNagarkattiPSNagarkattiM
Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates
Growth hormone plays a key role in regulating the bodys ability to burn fat for energy, and higher levels of growth hormone are associated with improved fat loss
The Role of Glycation Another factor in the aging of our tissues is "glycation," where sugar molecules attach to proteins like collagen, creating Advanced Glycation End-products (AGEs)
A 2023 phase II trial in 40 post-surgical patients found 0.5% GHK-Cu gel reduced scar volume by 35% at 3 months versus silicone (p=0.002) (Hosokawa et al., 2023)
Based on whether these cells stay alive without replicating, replicate, or die in the next time steps, the population can eventually either expand and grow exponentially or go extinct