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As we age, circulation to the scalp diminishes

Interestingly, in the same study, patients with MS with prolonged recorded somatosensory evoked potentials and prolonged visual evoked potentials had decreased B12 levels compared to patients with normal recorded values [121]

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Second, concerning oxidative stress and inflammation, butyrate enhances the activity of antioxidant defense systems such as superoxide dismutase, alleviating high-fat diet-induced hepatic oxidative damage and the expression of inflammatory factors [171], 172]

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Current Evidence Level Stating the evidence tier precisely, without softening: Weighing the positive and negative studies The positive human evidence is real but structurally weak, and the weakness is specific: nearly all of it comes from a single investigator group