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The addition of the acetyl group makes the molecule more lipophilic (fat-soluble), allowing it to interact uniquely with specialized transport proteins in the body, fundamentally changing where it can go and what it can do once it gets there
Aizenberg, P
The published record therefore reflects a proof-of-concept study that generated human safety and tolerability data while not meeting its primary endpoint as defined at the studied dose and population
Solution : Reconstitute one vial at a time, as needed
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