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- Enhances the body's natural detoxification mechanisms

4 Central GLP-1R pathways linking metabolic regulation and addiction circuits GLP-1 Rs are broadly distributed in brain circuits that play pivotal roles in motivation, including the striatum, hypothalamus, ventral tegmental area (VTA), and extended limbic regions such as the central amygdala and the infralimbic/prelimbic cortex (Pyke et al., 2014

NAD+ helps reduce inflammation

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In this study, twice-daily exenatide treatment was associated with a lower risk of CVD events including MI, ischemic stroke, or coronary revascularization procedure (hazard ratio [HR], 0.81

This might include: Adding SGLT2 inhibitors (such as dapagliflozin or empagliflozin), which work through a different mechanism by increasing urinary glucose excretion and offer cardiovascular and renal benefits