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Our study included 38 placebo-controlled trials, whose comparators included the medicines of acarbose, alogliptin, anagliptin, evogliptin, gemigliptin, linagliptin, omarigliptin, saxagliptin, sitagliptin, teneligliptin, trelagliptin, and vildagliptin

However, ten or more additional generic manufacturers may launch in 2025 providing a true, low-cost alternative GLP-1

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Furthermore, as these receptors are expressed both centrally and peripherally, it is clear that at least some of the adverse drug effects are due to antagonism of these receptors in peripheral tissues (Kimura et al., 2021)