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It is also a cautionary illustration of how much context a mechanism carries: the best-characterized KPV effect depends on an intestinal transporter (PepT1) abundant in gut epithelium, which is one reason KPV has been explored mainly for oral delivery in bowel inflammation rather than as a general-purpose systemic anti-inflammatory

Lancet 366(9498):17251735 Van Hove AH, Benoit DS (2015) Depot-based delivery systems for pro-angiogenic peptides: a review

It also found a possible revenue source: a paid size exchange program that would allow consumers one free size exchange within six months of purchase

Furthermore, most studies are limited to daily sampling and thus were not designed to address rapid changes that may occur within the endogenous metabolome of the individual in response to high-dose ingestion of APAP

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