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Blocking metallothionein-2 expression by copper-doped carbon dots induces cellular antioxidant system collapse for antitumor therapy

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When glutamate binds to its corresponding receptors (mainly NMDA, AMPA, and kainate receptors), sodium and calcium ions enter the postsynaptic neuron causing depolarization and therefore increasing the likelihood of an action potential, thus pressing the accelerator on the brain [8,9]