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This dependency is not limited to MYC-driven tumor cells but also occurs in various other cancer cell lines, including lymphomas, prostate cancer, osteosarcoma, renal cell carcinoma, colorectal cancer, and small cell lung cancer [84, 86,87,88,89,90].These tumor cells rely on glutamine for cell survival and growth when MYC is activated
Rasool A, Hafiz Shah W, Padder SA, Tahir I, Alharby HF, Hakeem KR (2022) Exogenous selenium treatment alleviates salinity stress in Proso Millet ( Panicum miliaceum L.) by enhancing the antioxidant defence system and regulation of ionic channels
In addition to the well-known effects of GLP-1 and GLP-1 RA in improving insulin sensitivity and reducing body weight, at central levels, GLP-1 and GLP-1 RA might exert regulating effects on GhRH release, and on concomitant gonadotropin secretion, likely by activating the kisspeptin hypothalamic system, a key regulator of the pulsatile release of GnRH from GnRH neurons
GLP-1 activation is also associated with delayed gastric emptying, another contributing factor to appetite suppression and thus reduced food intake
