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Theres just one small problem: not a single randomized controlled trial has ever been completed in humans

doi: 10.1111/cea.12860 [DOI] [PubMed] [Google Scholar] 42.Batty MJ, Chabrier G, Sheridan A, Gage MC

Note: Signs of low blood sugar include dizziness, shakiness, sweating, confusion, and a rapid heartbeat

Front Nutr 8:708096 Snchez Macarro M, vila-Ganda V, Prez-Piero S, Cnovas F, Garca-Muoz AM, Abelln-Ruiz MS et al (2021) Antioxidant effect of a probiotic product on a model of oxidative stress induced by high-intensity and duration physical exercise

To relieve this constipation you can stay hydrated, eat more fiber, exercise regularly, slow down and eat smaller meals, or take over the counter remedies like MiraLAX

A mechanistic review on how berberine use combats diabetes and related complications: molecular, cellular, and metabolic effects