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Chest 119:394401

In addition, SHMT2 depletion has been shown to induce mitochondrial respiratory chain deficiency by reducing basal respiration and respiratory capacity, decreasing NAD + /NADH ratios, and lowering the expression levels of respiratory complex I, IV, and V proteins [93]

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"Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase"

Decreased GSH levels have been shown to activate NFB, leading to a series of downstream signal transduction events that allow HIV expression [77]

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