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If you have cardiovascular concerns, anxiety disorders, or sleep disturbances, GLP-1 drugs present a safer choice since they don't activate your sympathetic nervous system
For injections, side effects often improve after a few weeks as your body adjusts
This is a significant concern for businesses who might be adversely affected by lower volumes of food sales to obese individuals
In summary, GLP-1RAs have the potential to inhibit neuroinflammation and promote nerve regeneration through the "Tregs-microglia-neuron/NPCs" axis: (1) GLP-1RAs directly and indirectly inhibit the activation of microglia, promote their M2 polarization, and secrete cytokines such as IL-4, IL-10, TGF - , IL-2 to exert anti-inflammatory effects (100)
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