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GLP-1/GIP assets primarily target obesity and type 2 diabetes indications, but are additionally in the late-stage pipeline for a broad scope of indications including chronic heart failure, osteoarthritis and liver fibrosis

Srkzy M, Kovcs ZZA, Kovcs MG, Gspr R, Szcs G, Dux L

Mitochondrial sirtuin 3 (SIRT3) is a major modulator of mitochondrial metabolism and homeostasis, regulating UPR mt , mitochondrial biogenesis, mitophagy, fusion/fission, and antioxidant expression 98

Recent reports suggest a possible link between ferroptosis and EBV reactivation, which is based on the observation of susceptibility to ferroptosis in EBV infections with different levels of activation 20

[DOI] [PubMed] [Google Scholar] 33.Yusta B., Baggio L.L., Estall J.L., Koehler J.A., Holland D.P., Li H., Pipeleers D., Ling Z., Drucker D.J