The closest is Qsymia, which combines phentermine with topiramate, but not with a GLP-1
Signs include dizziness, sweating, confusion, drowsiness, blurred vision, slurred speech, shakiness, rapid heartbeat, mood changes, and hunger
SDF-1 also plays a role in diabetes itself by protecting stem-cell-derived insulin-producing cells from glucotoxicity under high glucose conditions (70) or promoting pancreatic beta-cell survival in mice via Akt activation (71)
Katalin Karik and Prof
Other potential benefits of vitamin D on glucose metabolism may stem from its positive effects on mitochondrial function, oxidative stress, and epigenetic alterations in beta cells and other insulin-sensitive peripheral tissues (Vondra 2021)
Most patients continue to present with locally advanced disease, requiring aggressive multimodal therapy for curative intent [4,5,6]