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Celastrol, a widely used antioxidant drug, can reduce ROS accumulation by upregulating the Nrf2/GPX4 axis, thus significantly inhibiting ferroptosis of neurons and oligodendrocytes, thereby promoting the recovery of spinal cord tissue and motor function in rats with SCI

Neuropharmacology 55 , 12381250 (2008)

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US: research-use-only material, labeled not for human use

Furthermore, the intricate tapestry of long-term utilization, woven with threads of sustained efficacy, safety, and unforeseen consequences, merits detailed exploration, ensuring that the journey through metabolic management is not only immediately fruitful but also securely anchored in long-term well-being

& Ridderstrle, M