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Each serves a different purpose and comes with its own set of considerations

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Overall, although the overall absolute risk increase is small (27 cases per 10,000 persons treated per year), clinical practitioners should nevertheless take into account the potential risk of gallbladder or biliary diseases associated with GLP-1RAs, especially when used at higher doses, for longer durations, and for weight loss, and in case the patient has a history of lithiasis [64]

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BonDurant L, Potthoff M (2018) Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis

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Cardiovascular effects: For those who have or are predisposed to heart-related conditions like heart attacks and strokes, GLP-1 Shots-based medications may be more appealing

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