The possible negative influence of different doses of progoitrin on the thyroid was evaluated in humans using acute inhibition of radioiodine uptake, as well as 24 h uptake, by Greer et al
Always perform a patch test and follow manufacturer's instructions
As a general clinical principle: Retest HbA1c no sooner than three months after commencing B12 replacement therapy, and ideally once haematological recovery has been confirmed Confirm haematological recovery normalisation of MCV and haemoglobin before interpreting the repeat HbA1c as reliable Use interim glucose monitoring such as fasting plasma glucose, OGTT, or self-monitored blood glucose (SMBG) to assess glycaemic control during the treatment period
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Nature 437(7063):13701375
